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Using the Benchling Extension in Claude

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The Benchling integration connects Claude to Benchling R&D platform data, enabling scientists to ask questions and receive clear summaries with links back to source experiments, notebooks, and structured records—all while maintaining existing access permissions. This article explains how to set up and use the Benchling integration with Claude to advance your R&D workflows.

The Benchling integration is available as a desktop extension in the Claude Desktop App (download here), and it relies upon Claude's ability to use local connectors via a desktop extension.

What this integration provides

When Claude sends a query to Benchling, it can search across the full breadth of a customer’s Benchling environment. This covers experimental results and study data, notebook content such as text and attachments, and structured records like registry items, inventory, and templates. The Benchling integration brings these different data types together to provide a unified answer, saving scientists from having to manually piece information across entries or projects. You can also choose to pull in public literature sources, combining internal and external knowledge in one place. All results follow the same access permissions already set in Benchling, ensuring people only see the data they are meant to.

Who should use the Benchling integration

  • Bench Scientists & Research Associates - want to quickly find and summarize the right data, whether from Benchling or external sources, and use it to decide on next steps in their experiments.

  • Team Leads & Project Managers - need concise summaries of ongoing work and alignment with external findings to guide project planning.

  • Computational Biologists & Informatics Teams - want to ask governance questions and assemble curated datasets from Benchling that can be used for deeper analysis or shared across teams.

  • Program Leads - need automatically generated reports that combine Benchling study results with external context or public data, giving them a clear view of progress and next steps.

  • R&D Leaders & Executives - require portfolio-level insights to spot trends across programs and benchmark against public industry data.

Who can access the Benchling integration

Benchling customers who meet the following criteria:

  • Benchling AI (Deep Research) enabled in your tenant

  • API access (V3 APIs)

  • “Ask” functionality enabled

  • API key available for authentication

No additional setup is required beyond connecting Claude to the Benchling desktop extension and authenticating with your API key.

More details on accessing the integration can be found in Benchling’s MCP Server Documentation.

Setting up the Benchling integration

The Benchling integration is available as a desktop extension in the Claude Desktop App (download here). For Organization Owners (Team and Enterprise), setting up the integration involves making the extension available to your organization. For individual users, setting up the integration involves installing the extension from inside the Claude Desktop App.

For Organization Owners (Team and Enterprise)

  1. Navigate to Admin settings > Extensions

  2. In the search field, type “Benchling”

  3. Click “Enable”

  4. Instruct your team to download the Claude Desktop App to access the integration

For Individual Claude Users

  1. Download the Claude Desktop App

  2. Navigate to Settings > Extensions

  3. Click “Browse extensions”

  4. Click “Benchling”

  5. Click “Install”

  6. Follow the instructions to authenticate with your Benchling account details

For Claude Code Users

  1. Command: /plugin marketplace add anthropics/life-sciences

  2. Command: /plugin install benchling-mcp@life-sciences

  3. Restart Claude Code

  4. Command: /plugin

  5. Navigate to “Manage and uninstall plugins" and configure the Benchling MCP with your account details

  6. Restart Claude Code one more time

  7. Verify that the server is connected with /mcp

Technical details of the Benchling integration can be found in Benchling’s MCP Server Documentation.

Example use cases

  • Cross-Source Comparison: “Compare the IC50 results from my last two Benchling experiments with recent PubMed articles on AAV stability.”

  • Insight Summarization: “Summarize the key findings from Benchling experiments and highlight how they align with external literature trends.”

  • Recommendations: “Based on our last three in vivo results in Benchling and recent FDA guidance, what should we test next?”

  • Portfolio Insights: “Aggregate results from our top five Benchling programs and highlight which ones are showing the strongest early efficacy signals compared with industry benchmarks.”

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